Archive for September 2016

Monthly Archive

Autism and Ultrasound

Columbus3.docxThis  map reflects what the world was thinking when Christopher Columbus set out on his voyage to “discover” the New World. That’s kind of like where we are with Autism Spectrum Disorder (ASD). But there are many folks collaboratively engaged – parents, clinicians, educators, advocates, and scientists  – who are working to add details to the map.  

 

On the first of September researchers at Seattle Children’s and UW published a paper in Autism Research that identified a connection between exposure to diagnostic ultrasound in the first trimester of pregnancy and severity of autism symptoms observed in children diagnosed with autism. This connection was strongest when the children had certain genetic variations associated with ASD (called copy number variants). The paper has received some recent attention in the media so we wanted to take a moment to provide our take on the paper without any spin (one important caveat is that this blog author is one of the authors of the paper).

First and foremost, this study does not look at whether ultrasound causes autism or not. That is an important statement that should be clear. Given the way this study was designed, this question cannot be answered. Second, a key finding in this paper concerns the interaction between the genetic variations identified in the children, ultrasound, and the timing of exposure. The key point of the paper suggests there may be an interactive relationship between genetics and ultrasound exposure and the time of the exposure.

One more quick comment: this is the first paper to describe this interaction between ultrasound, genetics, timing and autism severity and therefore requires replication (repeat studies).  However, science requires independent replication. Additional studies are needed and, importantly, should be conducted by different research groups. Independent replication is critical to moving science forward.

So, what should we do with this information? We should put it on our map in pencil. We should consider it one step in our ongoing move toward a better understanding of ASD, which we’ll color in a little more with each independent replication – or we can erase it if there isn’t any replication. We can only keep filling in the landscape if we continue working together. As we’ve said in other studies on autism, we recommend a healthy dose of caution along with curiosity when reading about this study.

The Autism Blogcast with Jim and Raphe- September Edition

News Flash: The September edition of The Autism Blogcast, featuring autism experts Raphael Bernier, PhD and James Mancini, MS, CCC-SLP.

In an effort to keep you up to date on the latest news in research and community happenings, we welcome two of our favorite providers best known as Jim and Raphe, the autism news guys.

These two have too much energy to be contained in written format so our plan is to capture them in 2-5 minute videos that we’ll post the first week of each month. We welcome your questions and comments. Tell us what you think of our dynamic duo!

In this edition of the Blogcast, our reporters discuss book reviews regarding the history of autism and the important collaboration with family and science, as well as the state of universal screening for autism via Pediatricians and birth to three centers.